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杨中州
徐 璎
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夏焱博士实验室    

夏焱 PhD

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研究兴趣:

代表论文:

1. Pao, GM., Xia, Y., Verma, IM. and Hunter, T. “Functional roleof the mammalian SWI/SNF complex in the BRCA1 dependent DNA damage response pathway” manuscript to be submitted .

2. Xia Y., Wang J., Xu S., Liu TJ., Johnson G., Yung WK., Hunter T., and Lu Z. c-Jun Downregulation by HDAC3-Dependent Transcriptional Repression Promotes Osmotic Stress-induced Cell Apoptosis. Molecular Cell (2007) 25 : 219-232 (featured article).

 

3. Xia Y, Wang J, Xu S, Johnson G, Hunter T, and Lu Z. MEKK1 Mediates Ubiquitination and Degradation of c-Jun in Response to Osmotic Stress. (2007) Mol. Cell Biol.27 (2):510-517

     

4. Fang, D., Hawk, D., Zheng, YH., Xia, Y. Meisenhelder, J., Mills, G., Kobayashi, R., Hunter, T. and Lu, Z. “Phosphorylation of b-catenin by AKT promotes b-catenin Transcriptional activity” J. Biol. Chem., (2007) 282 : 11221-11229

 

5. Xia, Y., Pao, GM., Verma, IM.and Hunter, T. “Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein” (2003) J. Biol. Chem. 278 :5255-63.

 

6.  Xia, Y., Gally, D., Forsman-Semb, K. and Uhlin, B-E. “Regulatory cross-talk between adhesin operons in Escherichia coli: inhibition of type 1 fimbriae expression by the PapB protein” (2000) EMBO J. 19 : 1450-1457.

 

7.  Xia, Y., Forsman-Semb, K., Jass, J., and Uhlin, B-E. “Structural and functional studies of the fimbrial adhesin gene regulator PapB from uropathogenic Escherichia coli” Adv. Exp. Med. Biol. 2000; 485:123-6 (review)

 

8. Uhlin, B-E., Balsalobre, C., Forsman-Semb, K., Goransson, M., Jass, J., Johansson, J., Naureckiene, S., Sonden, B., Urbonaviciene, J., and Xia Y. “Control mechanisms in the Pap-pili system” Adv. Exp. Med. Biol. 2000;485:113-8 (review)

 

9. Xia, Y. and Uhlin, B-E. “Mutational analysis of transcriptional regulator PapB: regions important for DNA binding and oligomerization ” (1999) J. Biol. Chem. 274 : 19723-19730.

 

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