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高千博士实验室    

 

高千  PhD   教授

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研究方向: 遗传学。

 

代表论文

1.  Gao, Q. and Chess, A. (1999). Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics 60:31-39.

2.  Gao, Q., Yuan, B. and Chess, A. (2000). Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe. Nature Neuroscience 3(8):743-843.

3.  Gao, Q., Kano, A., Wolfgang, M., Jacoby, J., Chai, G.X., Hansen, W., Iwamoto,.Y., Pober, J.S., Flavell, R.A., and Fu. X.Y. (2003) Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. J Exp Med 198(10):1517-25. (co-first author).

4.  Jacoby, J.J., Kalinowski, A., Liu, M., Zhang, S.S., Gao, Q., Chai, G.X., Ji, L., Iwamoto, Y., Li, E., Schneider, M., Russell, K.S., Fu, X.Y. (2003),

5.  Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis and heart failure with advanced age. PNAS 100(22):12929-34.

6.   Gao, Q., Wolfgang, M.J., Neschen, S., Morino, K., Shulman, G.I., and Fu, X.Y. (2004), Disruption of neural STAT3 causes obesity, diabetes, infertility and thermal dysregulation. PNAS 101(13):4661-6.

7.  Gao, Q., Hua, J., Kimura, R, Headd, J.J., Fu, X.Y., Chin, Y.E. (2004). STAT-Like SH2 domain in plants: the origin of SH2 domain. Molecular and Cellular Proteomics 3(7):704-14

8.  Abizaid A, Gao Q, Horvath TL. Thoughts for food: brain mechanisms and peripheral energy balance. Neuron. 2006 Sep 21;51(6):691-702.

9.  Gao, Q., Mezei G., Bechmann I., Naftolin F., Leranth C., Borok E., Diano S., and Horvath T.L. (2007), Estradiol mimics leptin’s effect on synaptic plasticity of melanocortin cells in decreasing food intake and adiposity. Nature Medicine 13(1):89-94

10. Qian GaoTamas L. Horvath. 2007.Neurobiology of Feeding and Energy Expenditure. Annu. Rev. Neurosci. 30:367–98

 

 

 

 

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